Management of pheochromocytoma: old ideas and new drugs

Niger J Clin Pract. Jul-Sep 2012;15(3):253-7. doi: 10.4103/1119-3077.100616.

Abstract

Pheochromocytoma presents a challenge to the surgery team because of its clinical features and implications. The patient must be treated before the surgery until a stable hemodynamically state is achieved. The preoperative treatment includes α2-short acting adrenergic blocking and β-blocker agents. The most crucial intraoperative moments are induction of anesthesia and hemodynamic oscillations. An adequate preoperative preparation, modern anesthetic drugs, good collaboration between the surgeons and the anesthesiologists, and postoperative care decrease the rate of complications and improve the outcome. This review aims to discuss all the possible pharmacological strategies of perioperative management of phoechromocytoma, focusing on new drugs and treatments.

Publication types

  • Review

MeSH terms

  • Adrenal Gland Neoplasms / drug therapy
  • Adrenal Gland Neoplasms / physiopathology
  • Adrenal Gland Neoplasms / surgery
  • Adrenal Gland Neoplasms / therapy*
  • Adrenergic beta-Antagonists / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Hemodynamics
  • Humans
  • Intubation, Intratracheal
  • Perioperative Period
  • Pheochromocytoma / drug therapy
  • Pheochromocytoma / physiopathology
  • Pheochromocytoma / surgery
  • Pheochromocytoma / therapy*

Substances

  • Adrenergic beta-Antagonists
  • Antihypertensive Agents