Genotoxicity and development effects of brominated flame retardant PBDEs and UV-exposed PBDEs on grass shrimp (Palaemonetes pugio) embryo

Mar Pollut Bull. 2012 Dec;64(12):2892-5. doi: 10.1016/j.marpolbul.2012.08.010. Epub 2012 Sep 8.

Abstract

To understand how polybrominated diphenyl ethers (PBDEs) affect the hatching sensitivity of grass shrimp embryos in different developmental stages, the hatching rates of embryos were measured after PBDE exposure on the early- and late-stage embryo of grass shrimp. PBDEs had no clear influence on the hatching rate. Also, to investigate on the reproductive and genetic toxicities of UV-exposed PBDEs, the hatching rate and DNA damage of stage 7 embryos were also measured. PBDEs had no significant impact on the hatching rate and DNA damage of grass shrimp in most experimental conditions regardless of embryo developmental stage or UV exposure, but in the case of UV-exposed BDE-47, the hatching rate was decreased, suggesting a potential reproductive toxicity. This research is meaningful because it is the first study to propose that PBDEs can cause reproductive toxicity in marine organism, after flowing into the ocean and undergoing photochemical reactions stimulated by UV.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • DNA Damage
  • Embryo, Nonmammalian / drug effects*
  • Female
  • Flame Retardants / toxicity*
  • Growth and Development / drug effects
  • Halogenated Diphenyl Ethers / toxicity*
  • Mutagens / toxicity
  • Palaemonidae / embryology*
  • Polybrominated Biphenyls / toxicity
  • Water Pollutants, Chemical / toxicity*

Substances

  • Flame Retardants
  • Halogenated Diphenyl Ethers
  • Mutagens
  • Polybrominated Biphenyls
  • Water Pollutants, Chemical
  • 2,2',4,4'-tetrabromodiphenyl ether