A simple model for the immune network

Proc Natl Acad Sci U S A. 1990 Jan;87(1):429-33. doi: 10.1073/pnas.87.1.429.

Abstract

In this note I present a simple model for the idiotypic network among antibodies and study its relevance for the maintenance of immunological memory; in particular, the memory capacity of such a model is studied. Some of the similarities with the spin glass model and with neural networks are discussed.

MeSH terms

  • Animals
  • Immune System / immunology*
  • Immunoglobulin Idiotypes / immunology
  • Immunologic Memory*
  • Mathematics
  • Models, Biological*
  • Models, Neurological
  • Neurons / physiology

Substances

  • Immunoglobulin Idiotypes