Two-year results of translating the diabetes prevention program into an urban, underserved community

Diabetes Educ. 2012 Nov-Dec;38(6):798-804. doi: 10.1177/0145721712458834. Epub 2012 Sep 10.


Purpose: The purpose of the study was to examine the long-term effect of a Group Lifestyle Balance (GLB) program on weight, impaired fasting glucose, hypertension, and hyperlipidemia in an urban, medically underserved community.

Methods: This study was a single-arm prospective intervention study that was designed to test the effectiveness of a community-based GLB intervention. In sum, 638 residents from 11 targeted neighborhoods were screened for body mass index ≥ 25 kg/m(2) and metabolic syndrome. Eligible individuals took part in a 12-week GLB intervention (n = 105) that addressed weight loss and physical activity. Subjects were followed for 24 months.

Results: The probability of being at risk for diabetes and cardiovascular disease was significantly reduced by 25.7% over the long-term follow-up. Of the participants who lost at least 5% of their body weight following the intervention, 52.6% maintained the 5% weight loss at their last follow-up time, weighing about 20 lb less than they did at baseline.

Conclusion: Risk reduction and weight loss maintenance are possible following a GLB intervention and have substantial potential for future public health impact.

Publication types

  • Multicenter Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Glucose / metabolism*
  • Body Mass Index
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Diet, Reducing
  • Exercise
  • Female
  • Health Behavior
  • Humans
  • Hyperlipidemias / blood
  • Hyperlipidemias / epidemiology*
  • Hypertension / blood
  • Hypertension / epidemiology*
  • Male
  • Mass Screening
  • Medically Underserved Area*
  • Middle Aged
  • Patient Compliance
  • Patient Participation
  • Prediabetic State / blood
  • Prediabetic State / epidemiology*
  • Program Evaluation
  • Prospective Studies
  • Risk Factors
  • Treatment Outcome
  • United States / epidemiology
  • Urban Population
  • Weight Loss


  • Blood Glucose