Immune system polymorphisms and factor VIII inhibitor formation in Brazilian haemophilia A severe patients

Haemophilia. 2012 Nov;18(6):e416-8. doi: 10.1111/hae.12015. Epub 2012 Sep 13.

Authors

D Agostini¹, C Rosset, M R Botton, D B Kappel, I A Vieira, R P Gorziza, F M Salzano, E Bandinelli

Affiliation

¹ Departamento de Genética, Instituto de Biociências, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

PMID: 22970761
DOI: 10.1111/hae.12015

No abstract available

MeSH terms

Alleles
Brazil
CTLA-4 Antigen / genetics
Factor VIII / antagonists & inhibitors*
HLA-G Antigens / genetics
Hemophilia A / genetics*
Hemophilia A / immunology
Humans
Immune System / metabolism*
Interleukin-10 / genetics
Interleukin-4 / genetics
Odds Ratio
Polymorphism, Genetic*
Protein Tyrosine Phosphatase, Non-Receptor Type 22 / genetics
Receptors, Interleukin-4 / genetics
Receptors, Tumor Necrosis Factor, Type I / genetics
Severity of Illness Index
Tumor Necrosis Factor-alpha / genetics

Substances

CTLA-4 Antigen
CTLA4 protein, human
HLA-G Antigens
Receptors, Interleukin-4
Receptors, Tumor Necrosis Factor, Type I
Tumor Necrosis Factor-alpha
Interleukin-10
Interleukin-4
Factor VIII
PTPN22 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 22