Organelle signaling: how stressed chloroplasts communicate with the nucleus

Curr Biol. 2012 Sep 11;22(17):R690-2. doi: 10.1016/j.cub.2012.07.028.


Plastids are able to relay information to the nucleus to regulate stress responses. A new genetic screen has identified an isoprenoid intermediate that accumulates in stressed plastids and acts as a novel retrograde signal.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / physiology*
  • Cell Nucleus / metabolism*
  • Chloroplasts / metabolism*
  • Intracellular Signaling Peptides and Proteins / physiology
  • Metabolic Networks and Pathways
  • Phenotype
  • Plants, Genetically Modified / genetics
  • Plants, Genetically Modified / metabolism
  • Signal Transduction*
  • Stress, Physiological*


  • Intracellular Signaling Peptides and Proteins