Silent corticotroph adenomas of the pituitary gland: apropos of two cases

Endocrinol Nutr. 2008 Oct;55(8):367-71. doi: 10.1016/S1575-0922(08)72798-0. Epub 2008 Dec 25.
[Article in English, Spanish]

Abstract

Clinically silent corticotroph adenomas are rare. The clinical course of these tumors varies: while some have an insidious course, others behave aggressively, especially during tumoral recurrence. Given the absence of clinical and biochemical features of hypercortisolism, the definitive diagnosis is histological.