Transepithelial phototherapeutic keratectomy for recurrent corneal erosions in a patient with previous corneal collagen cross-linking

J Refract Surg. 2012 Oct;28(10):732-4. doi: 10.3928/1081597X-20120911-01. Epub 2012 Sep 17.


Purpose: To report the significant visual and topographic improvement of a patient who had corneal collagen cross-linking (CXL) performed and was subsequently treated with transepithelial phototherapeutic keratectomy (t-PTK) for recurrent corneal erosions.

Methods: A 36-year-old woman presented with recurrent corneal erosions in the right eye due to foreign body corneal trauma 1 month prior to presentation. The patient had undergone CXL treatment for keratoconus on the same eye 1 year prior to presentation. After failed conservative treatment consisting of epithelial debridement and lubrication with artificial tears, the patient underwent t-PTK.

Results: Four months after t-PTK, corneal erosions did not recur and the patient remained asymptomatic. Slit-lamp examination revealed a clear cornea. The patient showed significant visual and topographic improvement after t-PTK.

Conclusions: Transepithelial PTK for recurrent corneal erosions in a postoperative CXL patient successfully treated the corneal pathology, and visual and topographic improvement were observed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Collagen / metabolism*
  • Corneal Diseases / etiology
  • Corneal Diseases / physiopathology
  • Corneal Diseases / surgery*
  • Corneal Injuries
  • Corneal Pachymetry
  • Corneal Stroma / metabolism
  • Corneal Topography
  • Cross-Linking Reagents / therapeutic use*
  • Epithelium, Corneal
  • Eye Injuries, Penetrating / etiology
  • Female
  • Humans
  • Keratoconus / drug therapy*
  • Keratoconus / metabolism
  • Lasers, Excimer / therapeutic use*
  • Photorefractive Keratectomy*
  • Photosensitizing Agents / therapeutic use
  • Recurrence
  • Visual Acuity / physiology


  • Cross-Linking Reagents
  • Photosensitizing Agents
  • Collagen