An atypical growth of a giant fibroadenoma after trauma

J Pediatr Adolesc Gynecol. 2012 Oct;25(5):e115-7. doi: 10.1016/j.jpag.2012.06.004.


Background: Fibroadenomas are the most common benign breast lesion in female adolescents. However, it is important to recognize that a small percentage have been shown to progress to giant fibroadenomas. Giant fibroadenomas can spontaneously infarct leading to significant morbidity and are also difficult to distinguish from the more aggressive phyllodes tumors.

Case: We describe the first case, to the best of our knowledge, of a 12-year-old girl who presented with a giant fibroadenoma complicated by a central infarct and an intra-lesional hemorrhage from a trauma to the breast.

Summary and conclusion: The complicated giant fibroadenoma with an intra-lesional hemorrhage has characteristics of both benign and malignant lesions, and is difficult to distinguish by history and physical alone. Ultrasonography is a valuable tool yet the core needle biopsy remains the gold standard to confirm the diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Breast / injuries*
  • Breast Neoplasms / etiology
  • Breast Neoplasms / pathology*
  • Child
  • Diagnosis, Differential
  • Female
  • Fibroadenoma / etiology
  • Fibroadenoma / pathology*
  • Humans