Evidence-based practice: management of glottic cancer

Otolaryngol Clin North Am. 2012 Oct;45(5):1143-61. doi: 10.1016/j.otc.2012.06.014. Epub 2012 Jul 31.

Abstract

The main issue in the management of glottic squamous cell carcinoma, as for all cancers, is adequate disease control while optimizing functional outcomes and minimizing morbidity. This is true for early-stage disease as for advanced tumors. This article evaluates the current evidence for the diagnostic and pretherapeutic workup for glottic squamous cell carcinoma and the evidence concerning different treatment options for glottic carcinoma, from early-stage to advanced-stage disease.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell* / epidemiology
  • Carcinoma, Squamous Cell* / pathology
  • Carcinoma, Squamous Cell* / therapy
  • Chemotherapy, Adjuvant / methods
  • Chemotherapy, Adjuvant / statistics & numerical data
  • Combined Modality Therapy
  • Disease Management
  • Disease-Free Survival
  • Evidence-Based Practice*
  • Glottis* / pathology
  • Glottis* / surgery
  • Humans
  • Laryngeal Neoplasms* / epidemiology
  • Laryngeal Neoplasms* / pathology
  • Laryngeal Neoplasms* / therapy
  • Neck Dissection* / adverse effects
  • Neck Dissection* / methods
  • Neck Dissection* / statistics & numerical data
  • Neoplasm Grading
  • Neoplasm Recurrence, Local*
  • Neoplasm Staging
  • Otorhinolaryngologic Surgical Procedures* / adverse effects
  • Otorhinolaryngologic Surgical Procedures* / methods
  • Otorhinolaryngologic Surgical Procedures* / statistics & numerical data
  • Prognosis
  • Radiotherapy, Adjuvant / methods
  • Radiotherapy, Adjuvant / statistics & numerical data
  • Randomized Controlled Trials as Topic
  • Treatment Outcome