The effect of melatonin on the formation of gastric stress lesions in rats

R Khan; S Burton; S Morley; S Daya; B Potgieter

doi:10.1007/BF01955425

The effect of melatonin on the formation of gastric stress lesions in rats

Experientia. 1990 Jan 15;46(1):88-9. doi: 10.1007/BF01955425.

Authors

R Khan¹, S Burton, S Morley, S Daya, B Potgieter

Affiliation

¹ School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.

PMID: 2298286
DOI: 10.1007/BF01955425

Abstract

Prior melatonin administration (1,5 and 10 mg/kg b. wt) causes a significant reduction in gastric ulceration induced in male rats by restraint immobilization in the presence of low temperatures.

MeSH terms

Animals
Male
Melatonin / administration & dosage
Melatonin / pharmacology*
Rats
Rats, Inbred Strains
Restraint, Physical
Stomach Ulcer / etiology*
Stomach Ulcer / prevention & control
Stress, Physiological / complications*

Substances

Melatonin