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. 2012 Dec;83(8):1604-9.
doi: 10.1016/j.fitote.2012.09.009. Epub 2012 Sep 15.

Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities

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Sesquiterpenes from the aerial part of Chloranthus japonicus and their cytotoxicities

Mi Zhang et al. Fitoterapia. 2012 Dec.

Abstract

Four new sesquiterpenes, chlorajapolides F-I (1-4), along with nine known terpenoids (5-13) were isolated from the aerial part of Chloranthus japonicus. Their structures were elucidated on the basis of spectroscopic analysis, and a lindenane sesquiterpene, named 9-hydroxy-heterogorgiolide, previously isolated from the C. japonicus, was revised as its 8-epimer (1a). Moreover, methanol extract (ME), EtOAc fraction (EF), water fraction (WF), and all isolates (1a, 1-13) were evaluated for their cytotoxicities using two human cancer cell lines.

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