Abstract
Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Animals
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Antineoplastic Agents / administration & dosage
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Biocompatible Materials / chemistry
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Drug Carriers / chemistry
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Drug Delivery Systems*
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Humans
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Hydrogen-Ion Concentration
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Materials Testing
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Nanoparticles / chemistry*
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Nanotechnology
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Neoplasms, Experimental / drug therapy
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Oxidative Stress
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Polymers / chemistry
Substances
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Antineoplastic Agents
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Biocompatible Materials
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Drug Carriers
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Polymers