[Pharmacologic correction of hypoxia in patients with acute cerebral failure due to acute poisoning with carbon monoxide and combustion products]

Med Tr Prom Ekol. 2012;(6):22-7.
[Article in Russian]

Abstract

The article deals with the materials, which have been received in the process of the examination and treatment of 48 patients with acute severe carbon monoxide and burning products poisonings on fires. It has been registered that the including of citoflavin into the complex program of the intensive therapy of acute severe carbon monoxide and burning products poisonings on fires leads to a decrease of hypoxia and manifestations of acute toxicohypoxic cerebral deficiency, which significantly improves the clinics of acute severe poisonings.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acute Disease
  • Adult
  • Blood Gas Analysis
  • Carbon Monoxide Poisoning / complications
  • Carbon Monoxide Poisoning / drug therapy*
  • Combined Modality Therapy
  • Critical Care / methods
  • Drug Combinations
  • Drug Therapy, Combination
  • Female
  • Fires*
  • Flavin Mononucleotide / administration & dosage
  • Flavin Mononucleotide / therapeutic use*
  • Humans
  • Hypoxia / drug therapy*
  • Hypoxia / etiology
  • Hypoxia, Brain / drug therapy*
  • Hypoxia, Brain / etiology
  • Inosine Diphosphate / administration & dosage
  • Inosine Diphosphate / therapeutic use*
  • Male
  • Neuroprotective Agents / administration & dosage
  • Neuroprotective Agents / therapeutic use*
  • Niacinamide / administration & dosage
  • Niacinamide / therapeutic use*
  • Oxygen / blood
  • Respiration, Artificial
  • Succinates / administration & dosage
  • Succinates / therapeutic use*
  • Treatment Outcome

Substances

  • Drug Combinations
  • Neuroprotective Agents
  • Succinates
  • cytoflavin
  • Niacinamide
  • Flavin Mononucleotide
  • Inosine Diphosphate
  • Oxygen