Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study

Am J Obstet Gynecol. 2012 Dec;207(6):487.e1-9. doi: 10.1016/j.ajog.2012.08.034. Epub 2012 Sep 7.


Objective: This study aimed to prospectively examine the impact of chronic vs pregnancy-onset habitual snoring on gestational hypertension, preeclampsia, and gestational diabetes.

Study design: Third-trimester pregnant women were recruited from a large, tertiary medical center from March 2007 through December 2010 and screened for the presence and duration of habitual snoring, as a known marker for sleep-disordered breathing. Clinical diagnoses of gestational hypertension, preeclampsia, and gestational diabetes were obtained.

Results: Of 1719 pregnant women, 34% reported snoring, with 25% reporting pregnancy-onset snoring. After adjusting for confounders, pregnancy-onset, but not chronic, snoring was independently associated with gestational hypertension (odds ratio, 2.36; 95% confidence interval, 1.48-3.77; P < .001) and preeclampsia (odds ratio, 1.59; 95% confidence interval, 1.06-2.37; P = .024) but not gestational diabetes.

Conclusion: New-onset snoring during pregnancy is a strong risk factor for gestational hypertension and preeclampsia. In view of the significant morbidity and health care costs associated with hypertensive diseases of pregnancy, simple screening of pregnant women may have clinical utility.

MeSH terms

  • Adult
  • Case-Control Studies
  • Cohort Studies
  • Diabetes, Gestational / etiology*
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / etiology*
  • Incidence
  • Logistic Models
  • Odds Ratio
  • Pre-Eclampsia / etiology*
  • Pregnancy
  • Pregnancy Complications*
  • Pregnancy Trimester, Third
  • Prevalence
  • Prospective Studies
  • Snoring / etiology*
  • Young Adult