Universal influenza vaccine: the holy grail?

Expert Rev Vaccines. 2012 Aug;11(8):923-7. doi: 10.1586/erv.12.73.

Abstract

Influenza vaccines have been available since the 1950s and have seen increasingly wide use as public health authorities expanded recommendations. Recent events including shortages and avian influenza outbreaks have renewed interest in influenza vaccines, particularly improved vaccines.

MeSH terms

  • Adjuvants, Immunologic / chemistry
  • Antibodies, Viral / immunology
  • Antigens, Viral / immunology*
  • Biomedical Research / trends
  • Clinical Trials as Topic
  • Drug Industry / organization & administration
  • Hemagglutinin Glycoproteins, Influenza Virus / immunology
  • Humans
  • Influenza A virus / immunology*
  • Influenza A virus / pathogenicity
  • Influenza Vaccines / immunology*
  • Influenza, Human / immunology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Technology, Pharmaceutical / trends
  • Viral Matrix Proteins / immunology

Substances

  • Adjuvants, Immunologic
  • Antibodies, Viral
  • Antigens, Viral
  • Hemagglutinin Glycoproteins, Influenza Virus
  • Influenza Vaccines
  • M2 protein, Influenza A virus
  • Viral Matrix Proteins