The nuclear matrix of slowly and rapidly proliferating liver cells

Eur J Cell Biol. 1979 Dec;20(2):139-42.

Abstract

The nuclear matrix of slowly proliferating rat liver is compared with rapidly proliferating regenerating liver and Zajdela ascites hepatoma cells. While no differences are detected in overall ultrastructure, composition or polypeptide profiles of normal liver versus regenerating liver matrices, significant alterations are observed in the polypeptides of Zajdela hepatoma nuclear matrices.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Carcinoma, Hepatocellular / pathology*
  • Cell Division
  • Cell Nucleus / analysis
  • DNA / analysis
  • Liver / analysis
  • Liver / ultrastructure*
  • Liver Neoplasms / pathology*
  • Liver Regeneration*
  • Phospholipids / analysis
  • Proteins / analysis
  • RNA / analysis
  • Rats

Substances

  • Phospholipids
  • Proteins
  • RNA
  • DNA