Percentage of acute stroke patients eligible for endovascular treatment

Neurology. 2012 Sep 25;79(13 Suppl 1):S22-5. doi: 10.1212/WNL.0b013e31826957cf.


Endovascular treatment for acute ischemic stroke has the potential to substantially improve the outcome for select individual stroke patients. However, the impact of this treatment on a population scale is unknown. We reviewed the epidemiology of acute stroke presentation times to estimate the proportion of patients with ischemic stroke who may be eligible for intra-arterial treatment. Experience with IV thrombolysis suggests that time from symptom onset is likely to be among the major exclusion criteria for intra-arterial treatment. Studies reviewed suggest that between 5% and 13% of patients with ischemic stroke present in the commonly recommended intra-arterial treatment window of 3 to 6 hours. Because of clinical exclusion factors other than time, the proportion of stroke patients eligible for intra-arterial treatment is likely even lower than these estimates. Clinicians and researchers should consider this a modest proportion of eligible patients when planning future studies and creating referral networks for endovascular stroke treatment.

Publication types

  • Review

MeSH terms

  • Endovascular Procedures* / methods
  • Humans
  • Population Surveillance* / methods
  • Stroke / epidemiology
  • Stroke / therapy*
  • Thrombolytic Therapy* / methods
  • Treatment Outcome