The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management

Leuk Res. 2013 Feb;37(2):155-61. doi: 10.1016/j.leukres.2012.09.001. Epub 2012 Sep 27.


This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Directive Counseling*
  • Exercise Therapy*
  • Female
  • Humans
  • Leukemia / drug therapy
  • Leukemia / therapy*
  • Male
  • Mental Health
  • Middle Aged
  • Outpatients*
  • Pilot Projects
  • Quality of Life
  • Self Report
  • Treatment Outcome
  • Young Adult