Indications for keratoepithelioplasty

Arch Ophthalmol. 1990 Feb;108(2):233-6. doi: 10.1001/archopht.1990.01070040085036.


Thirteen patients with ocular surface failure were treated by keratoepithelioplasty using allografts of corneal limbal epithelial cells from donor eyes. The ocular surface was stabilized with long-term healing of persistent epithelial defects in five of eight eyes followed up for 4 to 19 months. The procedure was performed on an additional 5 patients with superficial keratopathies. Three of those five procedures resulted in a stable and clear optical surface. These results suggest that epithelial transplantation may be a useful option in the care of chronic ocular surface failure unresponsive to conventional medical management.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aniridia / complications
  • Cornea / surgery
  • Corneal Diseases / etiology
  • Corneal Diseases / surgery*
  • Epithelium / transplantation*
  • Eye Burns / complications
  • Female
  • Follow-Up Studies
  • Humans
  • Keratoplasty, Penetrating / adverse effects
  • Male
  • Methods
  • Middle Aged
  • Prognosis
  • Stevens-Johnson Syndrome / complications
  • Visual Acuity