The trans-frontal-sinus subcranial approach for removal of large olfactory groove meningiomas: surgical technique and comparison to other approaches

J Neurol Surg A Cent Eur Neurosurg. 2013 May;74(3):152-61. doi: 10.1055/s-0032-1325630. Epub 2012 Oct 1.


Background and study objective: Several surgical approaches have been previously reported for the treatment of olfactory groove meningiomas (OGM).The trans-frontal-sinus subcranial approach (TFSSA) for the removal of large OGMs is described, comparing it with other reported approaches in terms of advantages and drawbacks.

Material and methods: The TFSSA was performed on cadaveric specimens to illustrate the surgical technique.

Results: The surgical steps of the TFSSA and the related anatomical pictures are reported. The approach was adopted in a clinical setting; a case illustration is reported to demonstrate the feasibility of the described approach and to provide intraoperative pictures.

Conclusion: The TFSSA represents a possible route to treat large OGMs. The subcranial approach provides early devascularization of the tumor, direct tumor access from the base without traction on the frontal lobes, good overview of dissection of the optic nerves and anterior cerebral arteries, and dural reconstruction with pedicled pericranial flap.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms / surgery*
  • Cadaver
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Frontal Sinus / surgery*
  • Humans
  • Male
  • Meningioma / surgery*
  • Neurosurgical Procedures / methods*
  • Olfactory Bulb / surgery*
  • Skull Base / surgery
  • Surgical Flaps / surgery
  • Treatment Outcome