Calcium deposits in the perineurium and their relation to lipid accumulation

J Neurol Sci. 1979 Nov;43(3):367-75. doi: 10.1016/0022-510x(79)90016-9.


Calcification of the perineurium in sural nerves occurs in human adults. Deposits of calcium salts can be found focally in the middle and outer layers of the perineurium. Evidence indicates that this calcification is related to nerve fibre breakdown and to the local presence of lipids in the perineurium. The origin of the lipids may be senescent cells or degradation myelin.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Calcinosis / metabolism*
  • Calcinosis / pathology
  • Calcium / metabolism
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Lipid Metabolism*
  • Male
  • Middle Aged
  • Peripheral Nervous System Diseases / metabolism*
  • Peripheral Nervous System Diseases / pathology
  • Spinal Nerves / metabolism*
  • Sural Nerve / metabolism*
  • Sural Nerve / ultrastructure


  • Calcium