Joint effects of job strain and road-traffic and occupational noise on myocardial infarction

Scand J Work Environ Health. 2013 Mar 1;39(2):195-203. doi: 10.5271/sjweh.3324. Epub 2012 Oct 2.


Objectives: The aim of this study was to assess the joint effect of job strain and both road-traffic and occupational noise on myocardial infarction (MI).

Method: We conducted a population based case-control study on first time MI in Stockholm County during 1992-1994. Participants answered a questionnaire and underwent a physical examination. Residential road-traffic noise exposure was based on residential history combined with information on traffic intensity and distance to nearby roads. Occupational noise exposure was assessed by occupational history combined with a job-exposure matrix derived from measurements. Job strain was based on questions regarding psychological demands and decision latitude. A total of 3050 study participants (1252 cases and 1798 controls) were included in the study.

Results: An increased risk of MI was indicated among participants exposed to road-traffic noise [odds ratio (OR) 1.23, 95% confidence interval (95% CI) 1.01-1.51], occupational noise (OR 1.17, 95% CI 0.98-1.41) and job strain (OR 1.39, 95% CI 1.17-1.65). Participants exposed to one, two, or three of these factors showed an increased risk (OR 1.16, 95% CI 0.97-1.40, OR 1.57, 95% CI 1.24-1.98, and OR 2.27, 95% CI 1.41-3.64, respectively). Exposure to two or three of these factors occurred among about 20% of the controls.

Conclusion: Our results indicate that exposure to a combination of noise exposure and job strain increases the risk of MI substantially. Such exposures affect a considerable part of the population, which has relevance for prioritization of preventative measures.

MeSH terms

  • Aged
  • Air Pollution / adverse effects
  • Air Pollution / statistics & numerical data
  • Case-Control Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / epidemiology*
  • Myocardial Infarction / etiology
  • Noise, Occupational / adverse effects
  • Noise, Occupational / statistics & numerical data*
  • Noise, Transportation / adverse effects
  • Noise, Transportation / statistics & numerical data*
  • Occupational Exposure / adverse effects
  • Occupational Exposure / statistics & numerical data*
  • Stress, Psychological / epidemiology*
  • Sweden / epidemiology