Missing links? - The connection between replication and movement of plant RNA viruses

Curr Opin Virol. 2012 Dec;2(6):705-11. doi: 10.1016/j.coviro.2012.09.007. Epub 2012 Oct 1.

Abstract

Plant virus infection spreads from cell-to-cell within the host with the aid of viral movement proteins (MPs) that transport infectious genomes through intercellular pores called plasmodesmata (PD). MPs are able to accomplish RNA trafficking independent of virus infection. However, although dispensable for replication, they often associate with or assist in the formation of viral replication complexes. Quantitative analyses of genetic bottlenecks during infection, as well as considerations of transport specificity, suggest that intricate links between replication and movement may facilitate efficient delivery of plant viruses through PD during early infection, at a stage when viral genomes are still rare.

Publication types

  • Review

MeSH terms

  • Plant Viral Movement Proteins / metabolism*
  • Plant Viruses / pathogenicity
  • Plant Viruses / physiology*
  • Plants / virology
  • Plasmodesmata / metabolism
  • Plasmodesmata / virology
  • RNA Viruses / pathogenicity
  • RNA Viruses / physiology*
  • RNA, Viral / metabolism*
  • Virus Replication*

Substances

  • Plant Viral Movement Proteins
  • RNA, Viral