Comparison of the MGIT TBc immunochromatographic assay with the Accuprobe Gen-Probe TB assay for identification of Mycobacterium tuberculosis complex: results from a low-burden tuberculosis setting

Sally A Roberts; Odette Lowe; Sushil Pandey; Deborah A Williamson; Sandie Newton; Ross Vaughan

doi:10.1016/j.diagmicrobio.2012.08.007

Comparison of the MGIT TBc immunochromatographic assay with the Accuprobe Gen-Probe TB assay for identification of Mycobacterium tuberculosis complex: results from a low-burden tuberculosis setting

Diagn Microbiol Infect Dis. 2012 Dec;74(4):415-6. doi: 10.1016/j.diagmicrobio.2012.08.007. Epub 2012 Oct 1.

Authors

Sally A Roberts¹, Odette Lowe, Sushil Pandey, Deborah A Williamson, Sandie Newton, Ross Vaughan

Affiliation

¹ Mycobacteria Section, Department of Microbiology, Auckland District Health Board, Auckland New Zealand. sallyrob@adhb.govt.nz

PMID: 23036825
DOI: 10.1016/j.diagmicrobio.2012.08.007

Abstract

We compared the BD MPT64 TBc Antigen assay with the Gen-Probe TB assay for identifying Mycobacterium tuberculosis (MTB) from liquid culture vials. The BD TBc Antigen assay was more sensitive than and as specific as the Gen-Probe TB assay, making it a useful alternative for the rapid detection of MTB.

Publication types

Comparative Study
Evaluation Study

MeSH terms

Bacteriological Techniques / methods
Chromatography, Affinity / methods*
Humans
Molecular Diagnostic Techniques / methods*
Mycobacterium tuberculosis / genetics
Mycobacterium tuberculosis / immunology
Mycobacterium tuberculosis / isolation & purification*
Sensitivity and Specificity
Tuberculosis / diagnosis*