Burn injuries
- PMID: 23037877
- DOI: 10.1097/MCC.0b013e328359fd6e
Burn injuries
Abstract
Purpose of review: To summarize and highlight recent advances in the understanding and management of burn injuries.
Recent findings: The review focuses on topics which are of particular relevance for critical care practitioners involved in burn care: resuscitation, management of infection and sepsis, epidemiology and outcome, and organization and costs of burn care.
Summary: While being the mainstay of early survival in burn victims, various aspects of burn resuscitation are still contentious and highlighted in this review. In particular, several strategies to overcome the repeatedly observed 'fluid creep' in burn patients are discussed, including the use of computerized resuscitation algorithms and the administration of colloids. Sepsis and multiorgan failure have become the major causes of death in patients surviving the initial phase of burn shock. Various aspects of sepsis management are reviewed, amongst which diagnosis, antibiotic treatment and prophylaxis. Recent epidemiologic data allow to identify risk factors associated with mortality as these are potentially amenable to targeted prevention and therapy. Examples are acute kidney injury and sepsis. The overview is completed by recent findings on organization and costs of burn care, including the adherence to referral criteria and the main determinants of cost.
Similar articles
-
Update on the critical care management of severe burns.J Intensive Care Med. 2011 Jul-Aug;26(4):223-36. doi: 10.1177/0885066610390869. J Intensive Care Med. 2011. PMID: 21764766
-
Management of acute burns and burn shock resuscitation.AACN Clin Issues Crit Care Nurs. 1993 May;4(2):351-66. AACN Clin Issues Crit Care Nurs. 1993. PMID: 8489882
-
Burn management.Curr Opin Crit Care. 2011 Dec;17(6):601-5. doi: 10.1097/MCC.0b013e32834c563f. Curr Opin Crit Care. 2011. PMID: 21986459 Review.
-
Advances in surgical care: management of severe burn injury.Crit Care Med. 2008 Jul;36(7 Suppl):S318-24. doi: 10.1097/CCM.0b013e31817e2d64. Crit Care Med. 2008. PMID: 18594259 Review.
-
Management of war-related burn injuries: lessons learned from recent ongoing conflicts providing exceptional care in unusual places.J Craniofac Surg. 2010 Sep;21(5):1529-37. doi: 10.1097/SCS.0b013e3181f3ed9c. J Craniofac Surg. 2010. PMID: 20818237
Cited by
-
Altered adrenal and gonadal steroids biosynthesis in patients with burn injury.Clin Mass Spectrom. 2016 Oct 26;1:19-26. doi: 10.1016/j.clinms.2016.10.002. eCollection 2016 Nov. Clin Mass Spectrom. 2016. PMID: 39193421 Free PMC article.
-
Demographic Assessment of Burn Injuries in Iranian Patients.Bull Emerg Trauma. 2024;12(1):26-34. doi: 10.30476/BEAT.2024.99775.1456. Bull Emerg Trauma. 2024. PMID: 38689794 Free PMC article.
-
Effect of albumin substitution on pharmacokinetics of piperacillin/tazobactam in patients with severe burn injury admitted to the ICU.J Antimicrob Chemother. 2024 Feb 1;79(2):262-270. doi: 10.1093/jac/dkad368. J Antimicrob Chemother. 2024. PMID: 38069908 Free PMC article.
-
Application of Phagotherapy in the Treatment of Burn Patients (Review).Sovrem Tekhnologii Med. 2021;12(3):95-103. doi: 10.17691/stm2020.12.3.12. Epub 2020 Jun 28. Sovrem Tekhnologii Med. 2021. PMID: 34795985 Free PMC article. Review.
-
The Bactericidal Tandem Drug, AB569: How to Eradicate Antibiotic-Resistant Biofilm Pseudomonas aeruginosa in Multiple Disease Settings Including Cystic Fibrosis, Burns/Wounds and Urinary Tract Infections.Front Microbiol. 2021 Jun 17;12:639362. doi: 10.3389/fmicb.2021.639362. eCollection 2021. Front Microbiol. 2021. PMID: 34220733 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials
