Friction blisters and sock fiber composition. A double-blind study

J Am Podiatr Med Assoc. 1990 Feb;80(2):63-71. doi: 10.7547/87507315-80-2-63.


A longitudinal double-blind study was conducted to determine the effect of sock fiber composition on the frequency and size of blistering events in long-distance runners. Thirty-five long-distance runners participated in this study. Two different socks were tested, which were identical in every aspect of construction except fiber composition. One test sock was composed of 100% acrylic fibers, and the other test sock was composed of 100% natural cotton fibers. The results showed that acrylic fiber socks were associated with fewer blistering events and smaller blisters (mm2), when compared directly to cotton fiber socks.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylates
  • Adult
  • Blister / prevention & control*
  • Clothing*
  • Double-Blind Method
  • Female
  • Foot Dermatoses / prevention & control*
  • Gossypium
  • Humans
  • Longitudinal Studies
  • Male
  • Running / injuries*


  • Acrylates