Lethal intratumoral haemorrhages of brain metastases during radiosurgery: case reports and literature review

Acta Neurochir (Wien). 2013 Jan;155(1):115-8. doi: 10.1007/s00701-012-1507-x. Epub 2012 Sep 30.

Abstract

Gamma Knife surgery (GKS) is an effective and important treatment modality in the management of brain metastases. The short-term complication rate is low and the tumour control rate high. Complications caused by acute radiation-induced oedema are rare and usually benign. In this article, two cases of lethal haemorrhagic event immediately following GKS are described from two centres, which had prompted us to review the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Brain Neoplasms / mortality
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / surgery*
  • Carcinoma, Non-Small-Cell Lung / mortality
  • Carcinoma, Non-Small-Cell Lung / secondary*
  • Carcinoma, Non-Small-Cell Lung / surgery*
  • Fatal Outcome
  • Female
  • Humans
  • Intracranial Hemorrhages / etiology*
  • Intracranial Hemorrhages / mortality
  • Lung Neoplasms / mortality
  • Lung Neoplasms / pathology
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Radiosurgery / adverse effects*