Focal cortical thinning is caused by remote subcortical infarcts: spooky action at a distance

Neurology. 2012 Nov 13;79(20):2016-7. doi: 10.1212/WNL.0b013e3182749f6e. Epub 2012 Oct 10.

Abstract

In this issue of Neurology®, Duering et al.(1) present compelling proof-of-principle evidence that small subcortical infarcts have remote consequences on gray matter volume. Using MRI scans acquired before and after an incident subcortical infarct, they were able to show that the appearance of a new subcortical infarct was associated with cortical thinning in connected brain regions.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Cerebral Cortex / pathology*
  • Cerebral Infarction / pathology*
  • Female
  • Humans
  • Male
  • Nerve Fibers, Myelinated / pathology*