Using "smart stimulators" to treat Parkinson's disease: re-engineering neurostimulation devices

Front Comput Neurosci. 2012 Sep 21;6:69. doi: 10.3389/fncom.2012.00069. eCollection 2012.


Let's imagine the cruise control of your car locked at 120 km/h on any road in any condition (city, country, highway, sunny or rainy weather), or your car air conditioner set on maximum cold in any temperature condition (even during a snowy winter): would you find it efficient? That would probably not be the most optimal strategy for a proper and comfortable driving experience. As surprising as this may seem, this is a pretty accurate illustration of how deep brain stimulation is used today to treat Parkinson's disease motor symptoms and other neurological disorders such as essential tremor, obsessive-compulsive disorder, or epilepsy.

Keywords: Parkinson’s disease; deep brain stimulation; mathematical models; medical devices; neuroengineering.