Two new pregnane glycoside diesters from Caralluma russeliana

Nat Prod Res. 2013;27(14):1287-92. doi: 10.1080/14786419.2012.733390. Epub 2012 Oct 15.

Abstract

Two new pregnane glycoside diesters, 1 and 2, in addition to two triterpenoids, 3 and 4, and two sterols, 5 and 6 were isolated and identified from Caralluma russeliana (family Asclepiadaceae). The new pregnane glycosides, 14β-benzoyloxy-15β-isovaleroyloxy-16α-hydroxypregn-20-on-3-O-[β-D-3-O-methyl-6-deoxyoleandrosopyranosyl-(1 → 4)-β-D-cymaropyranosyl-(1 → 4)-β-D-cymaropyranoside] (1) and 14β-isovaleroyloxy-15β-benzoyloxy-16α-hydroxypregn-20-on-3-O-[β-D-3-O-methyl-6-deoxyoleandrosopyranosyl-(1 → 4)-β-D-cymaropyranosyl-(1 → 4)-β-D-cymaropyranoside] (2), are different from those isolated previously from the same species in the sugar moiety, in being diester, in being 20-one and in being 5,6 saturated by hydrogen. The isolated compounds were identified on the basis of spectral data.

MeSH terms

  • Apocynaceae / chemistry*
  • Chloroform
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Phytosterols / chemistry
  • Phytosterols / isolation & purification
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification*
  • Pregnanes / chemistry
  • Pregnanes / isolation & purification*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification

Substances

  • Glycosides
  • Phytosterols
  • Plant Extracts
  • Pregnanes
  • Triterpenes
  • pregnane glycoside
  • Chloroform