The impact of slower walking speed on activities of daily living in patients with multiple sclerosis

Int J Clin Pract. 2012 Nov;66(11):1088-94. doi: 10.1111/ijcp.12003.

Abstract

Aims: To identify the relevance and impact of walking speed (WS) over a short distance on activities of daily living (ADLs) in patients with multiple sclerosis (MS).

Methods: An internet-administered survey of MS patients in four countries was distributed to 605 individuals in 2010. Participants had MS for > 5 years and must have reported difficulty walking as a result of MS. The impact of MS on walking and the effects of WS on ADLs were assessed based upon responses (scored on a scale of 1-10) to five questions and categorised post hoc as: high (8-10), moderate (4-7) or low (1-3) impact/importance.

Results: Of the participants who completed the survey (n = 112), 60% were female patients, 63% were aged ≥ 45 years, and 55% had relapsing-remitting MS. Approximately, half of participants reported a high impact of MS on their general walking ability (46%) and their ability to increase WS over a short distance (55%). Up to 53% of participants reported avoiding ADLs because of concerns about WS; within this cohort, older male patients and patients with secondary-progressive MS were highly represented.

Discussion: These results, which highlight the importance of WS to patients with MS and emphasise the impact of WS on health-related quality of life and ADLs, underscore the importance of clinical measures of WS, such as the timed 25-foot walk, in assessing walking in MS patients.

Conclusion: Walking speed over a short distance has a significant impact on ADLs for patients with MS.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living*
  • Adult
  • Aged
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multiple Sclerosis / physiopathology*
  • Multiple Sclerosis / rehabilitation
  • Quality of Life
  • Surveys and Questionnaires
  • Walking / physiology*