Promotion of the efficient metabolic maturation of human pluripotent stem cell-derived hepatocytes by correcting specification defects

Cell Res. 2013 Jan;23(1):157-61. doi: 10.1038/cr.2012.144. Epub 2012 Oct 16.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Differentiation
  • Cells, Cultured
  • Hepatocyte Nuclear Factor 3-beta / genetics
  • Hepatocyte Nuclear Factor 3-beta / metabolism
  • Hepatocyte Nuclear Factor 4 / genetics
  • Hepatocyte Nuclear Factor 4 / metabolism
  • Hepatocyte Nuclear Factor 6 / genetics
  • Hepatocyte Nuclear Factor 6 / metabolism
  • Hepatocytes / cytology
  • Hepatocytes / metabolism*
  • Homeodomain Proteins / genetics
  • Homeodomain Proteins / metabolism
  • Humans
  • Pluripotent Stem Cells / cytology*
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism

Substances

  • FOXA2 protein, human
  • HNF4A protein, human
  • Hepatocyte Nuclear Factor 4
  • Hepatocyte Nuclear Factor 6
  • Homeodomain Proteins
  • ONECUT1 protein, human
  • Tumor Suppressor Proteins
  • prospero-related homeobox 1 protein
  • Hepatocyte Nuclear Factor 3-beta