Etiologies of septic shock in a pediatric emergency department population

Pediatr Infect Dis J. 2012 Nov;31(11):1203-5. doi: 10.1097/INF.0b013e3182678ca9.


Knowledge of pediatric sepsis etiologies is needed to optimize empiric therapy. A retrospective cross-sectional review of 428 children with clinically diagnosed sepsis found that 13% had lobar pneumonia, 12% bacteremia and 10% viral infections. No etiologies were found in 76%. Empiric antibiotic coverage of vancomycin/piperacillin-tazobactam/gentamicin for immunocompromised children and vancomycin/nafcillin/cefotaxime for previously healthy children would have covered all bacteremic children.

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Retrospective Studies
  • Shock, Septic / drug therapy*
  • Shock, Septic / microbiology*


  • Anti-Bacterial Agents