Interface lamellar keratitis induced by a post-Descemet stripping automated endothelial keratoplasty corneal trauma

Cornea. 2013 Mar;32(3):362-4. doi: 10.1097/ICO.0b013e3182656866.


A 78-year-old female patient suffering from Fuchs endothelial dystrophy had uneventful Descemet stripping automated endothelial keratoplasty (DSAEK) on the right eye. One and a half months postoperatively, she underwent a corneal foreign body trauma and was referred to our clinic, complaining about vision deterioration. Slit-lamp examination revealed a severe and diffuse interface lamellar keratitis between the DSAEK graft and the recipient's cornea without any signs of graft dysfunction. Intensive treatment with local corticosteroids was applied immediately, resulting in prompt improvement of both visual acuity and clinical condition. A new clinical entity, described as interface lamellar keratitis after corneal trauma in a DSAEK patient, is presented. Early diagnosis and appropriate intensive treatment with local corticosteroids are essential to successfully address this uncommon post-DSAEK complication.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cell Count
  • Corneal Injuries*
  • Corneal Pachymetry
  • Descemet Stripping Endothelial Keratoplasty*
  • Dexamethasone / therapeutic use
  • Endothelium, Corneal / pathology
  • Eye Foreign Bodies / etiology*
  • Eye Injuries, Penetrating / etiology*
  • Female
  • Fuchs' Endothelial Dystrophy / surgery*
  • Glucocorticoids / therapeutic use
  • Humans
  • Keratitis / diagnosis
  • Keratitis / drug therapy
  • Keratitis / etiology*
  • Microscopy, Confocal
  • Middle Aged
  • Postoperative Period
  • Tomography, Optical Coherence
  • Visual Acuity / physiology


  • Glucocorticoids
  • Dexamethasone