Bioactive oleanane, lupane and ursane triterpene acid derivatives

Molecules. 2012 Oct 17;17(10):12197-205. doi: 10.3390/molecules171012197.

Abstract

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Artemia / drug effects
  • Esters / chemistry
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / pharmacology
  • Lamiaceae / chemistry
  • Nuclear Magnetic Resonance, Biomolecular
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / pharmacology*
  • Pentacyclic Triterpenes
  • Plant Extracts / chemistry
  • Triterpenes / chemistry
  • Triterpenes / pharmacology*

Substances

  • Esters
  • Free Radical Scavengers
  • Pentacyclic Triterpenes
  • Plant Extracts
  • Triterpenes
  • betulinic acid
  • Oleanolic Acid
  • ursolic acid