Metal-on-metal hips: cobalt can induce an endotoxin-like response

Ann Rheum Dis. 2013 Mar;72(3):460-1. doi: 10.1136/annrheumdis-2012-202468. Epub 2012 Oct 17.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaline Phosphatase / biosynthesis*
  • Animals
  • Cell Line
  • Cobalt / adverse effects*
  • Hip Prosthesis / adverse effects*
  • Humans
  • Mice
  • Toll-Like Receptor 4 / metabolism*

Substances

  • TLR4 protein, human
  • Toll-Like Receptor 4
  • Cobalt
  • Alkaline Phosphatase