A novel approach to develop anti-virulence agents against group A streptococcus

Virulence. 2012 Aug 15;3(5):452-3. doi: 10.4161/viru.21039. Epub 2012 Aug 15.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Disease Models, Animal
  • Enzyme Inhibitors / pharmacology
  • Gene Expression Regulation, Bacterial / drug effects
  • Humans
  • Mice
  • Mice, Transgenic
  • Quinazolines / pharmacology
  • Streptococcal Infections / microbiology
  • Streptococcus pyogenes / drug effects
  • Streptococcus pyogenes / genetics
  • Streptococcus pyogenes / pathogenicity*
  • Streptokinase / antagonists & inhibitors*
  • Streptokinase / metabolism*
  • Virulence
  • Virulence Factors / antagonists & inhibitors*
  • Virulence Factors / metabolism*

Substances

  • Anti-Bacterial Agents
  • CCG-2979
  • Enzyme Inhibitors
  • Quinazolines
  • Virulence Factors
  • Streptokinase