Frailty is associated with longer hospital stay and increased mortality in hospitalized older patients

J Nutr Health Aging. 2012 Aug;16(8):732-5. doi: 10.1007/s12603-012-0369-5.


Introduction: With the onset of frailty, there is often a rapid, progressive, and self- perpetuating downward spiral towards death. Frailty has enormous impact on acute hospital care and has been shown to be a more effective predictor of mortality than conventional clinical measures.

Methods: Hospitalized older patients admitted in medical wards at a teaching public hospital were studied to determine the prevalence of frailty; its association with anemia, congestive heart failure, clinically active tuberculosis and cognitive impairment; as well as its impact upon short-term outcome.

Results: A total of 250 older hospitalized patients were included, and their frailty status was assessed using Fried's criteria. Of these, 83 (33.2%) patients were frail, with frailty found to be significantly associated with increasing age. A lower mean level of haemoglobin (p, 0.002), higher chance of congestive heart failure (p, <0.001), lower mean MMSE score (p, <0.001), was found in frail older patients. Frail subjects had a higher median hospital stay. There were total of 5 deaths, all among the frail group.

Conclusion: Our study showed that almost a third of hospitalized older patients are frail, and have anemia, higher frequency of CHF, cognitive impairment, longer hospital stay and higher mortality.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging*
  • Anemia / diagnosis
  • Anemia / epidemiology*
  • Anemia / ethnology
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / ethnology
  • Female
  • Frail Elderly*
  • Heart Failure / diagnosis
  • Heart Failure / epidemiology*
  • Heart Failure / ethnology
  • Hospital Mortality / ethnology
  • Hospitals, Public
  • Hospitals, Teaching
  • Humans
  • Incidence
  • India / epidemiology
  • Length of Stay
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Survival Analysis