Schizophrenic individuals with bipolar first-degree relatives: analysis of two pedigrees

J Clin Psychiatry. 1990 Mar;51(3):97-101.


During the course of a family-interview study of probands with psychotic disorders, the authors encountered two pedigrees in which schizophrenic individuals had first-degree relatives with bipolar disorder. The authors describe the members of both families in detail and discuss several hypotheses that might account for the co-occurrence of schizophrenia and bipolar disorder in the same family.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Bipolar Disorder / complications
  • Bipolar Disorder / diagnosis
  • Bipolar Disorder / genetics*
  • Diagnostic Errors
  • Family*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pedigree
  • Psychiatric Status Rating Scales
  • Risk Factors
  • Schizophrenia / complications
  • Schizophrenia / diagnosis
  • Schizophrenia / genetics*
  • Schizophrenic Psychology
  • Sex Factors