Extremely drug-resistant Salmonella enterica serovar Senftenberg infections in patients in Zambia

J Clin Microbiol. 2013 Jan;51(1):284-6. doi: 10.1128/JCM.02227-12. Epub 2012 Oct 17.


Two cases of extremely drug-resistant Salmonella enterica serovar Senftenberg isolated from patients in Zambia were investigated by utilizing MIC determinations and whole-genome sequencing. The isolates were resistant to, and harbored genes toward, nine drug classes, including fluoroquinolones and extended-spectrum cephalosporins, contained two plasmid replicons, and differed by 93 single-nucleotide polymorphisms.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Drug Resistance, Multiple, Bacterial*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Plasmids
  • Polymorphism, Single Nucleotide
  • Salmonella Infections / microbiology*
  • Salmonella enterica / drug effects*
  • Salmonella enterica / genetics
  • Salmonella enterica / isolation & purification*
  • Zambia


  • Anti-Bacterial Agents