Spastic paraparesis and sensorineural hearing loss in a patient with neurobrucellosis

J Back Musculoskelet Rehabil. 2012;25(3):157-9. doi: 10.3233/BMR-2012-0322.

Abstract

Objective: Brucellosis is a zoonotic disease and still a major public health problem in many geographic areas including Mediterranean basin and Middle East. Brucellosis causes multisystemic involvement and although rare central nervous system involvement causes serious manifestations. Neurobrucellosis occurs less than 5% of patients and presents with meningitis,encephalitis, myelitis, myelopathy, stroke, paraplegia, radiculoneuritis, intracerebral abscess, epidural abscess, demyelination and cranial nerve involvement or any combination of these manifestations. Spastic paraparesis and the sensorineural involvement are rarely reported in the literature.

Methods: Herein we present a 28 years-old man with spastic paraparesis and sensorineural hearing loss due to neurobrucellosis.

Results: The patient was treated with antibiotics combination for 6 months and underwent rehabilitation program.

Conclusions: Neurobrucellosis should be ruled out in patients with unexplained neurological symptoms and/or sensorineuralhearing loss particularly in those living in endemic areas.

Publication types

  • Case Reports

MeSH terms

  • Adrenoleukodystrophy / diagnosis
  • Adrenoleukodystrophy / etiology*
  • Adrenoleukodystrophy / rehabilitation
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Brucellosis / complications*
  • Brucellosis / diagnosis
  • Brucellosis / drug therapy
  • Central Nervous System Bacterial Infections / complications*
  • Central Nervous System Bacterial Infections / diagnosis
  • Central Nervous System Bacterial Infections / drug therapy
  • Deafness / diagnosis
  • Deafness / etiology*
  • Deafness / rehabilitation
  • Doxycycline / therapeutic use
  • Genetic Diseases, X-Linked / diagnosis
  • Genetic Diseases, X-Linked / etiology*
  • Genetic Diseases, X-Linked / rehabilitation
  • Hearing Loss, Sensorineural / diagnosis
  • Hearing Loss, Sensorineural / etiology*
  • Humans
  • Male
  • Muscle Spasticity / diagnosis
  • Muscle Spasticity / etiology*
  • Muscle Spasticity / rehabilitation
  • Paralysis / diagnosis
  • Paralysis / etiology*
  • Paralysis / rehabilitation
  • Treatment Outcome
  • Turkey

Substances

  • Anti-Bacterial Agents
  • Doxycycline

Supplementary concepts

  • Wells Jankovic syndrome