Diagnosis of celiac disease

Gastrointest Endosc Clin N Am. 2012 Oct;22(4):661-77. doi: 10.1016/j.giec.2012.07.004. Epub 2012 Aug 20.


This article reviews issues related to identifying the appropriate patient to test for celiac disease, the performance characteristics of serologic testing, the role of gene testing for human leukocyte antigen DQ2 and DQ8 haplotypes, and issues related to the performance of small intestinal biopsy. The article concludes with a review of special diagnostic considerations in pediatric patients.

Publication types

  • Review

MeSH terms

  • Antibodies / blood
  • Autoantibodies / blood
  • Biopsy
  • Celiac Disease / diagnosis*
  • Endoscopy, Digestive System
  • Genetic Testing
  • HLA-DQ Antigens / genetics
  • Humans
  • Intestine, Small / pathology
  • Mass Screening


  • Antibodies
  • Autoantibodies
  • HLA-DQ Antigens