Toxic epidermal necrolysis in a 15-month-old girl successfully treated with amniotic membrane transplantation

J AAPOS. 2012 Oct;16(5):478-80. doi: 10.1016/j.jaapos.2012.05.011.

Abstract

A 15-month-old girl presented with rash, fever, and vesicles around the mouth that worsened after erythromycin was administered. Subsequently, she was diagnosed with toxic epidermal necrolysis. Ocular involvement was treated with repeated complete corneal, conjunctival, and lid margin coverage with amniotic membrane. She recovered with minimal ocular sequelae despite persistent systemic symptoms.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Amnion / transplantation*
  • Conjunctival Diseases / therapy
  • Corneal Diseases / therapy
  • Eye Diseases / surgery*
  • Eyelid Diseases / therapy
  • Female
  • Humans
  • Infant
  • Stevens-Johnson Syndrome / surgery*
  • Treatment Outcome