Report of 7 Uterine Rupture Cases After Laparoscopic Myomectomy: Update of the Literature

J Minim Invasive Gynecol. Nov-Dec 2012;19(6):762-7. doi: 10.1016/j.jmig.2012.07.003.


The objective of this article is to report 7 previously unpublished uterine rupture cases in pregnancy after laparoscopic myomectomy and to update the medical literature. All cases were reported to the Board of Endoscopic Gynecologic Surgery (Athens, Greece) from 1998 to 2011. Myomas were single in 85.7% of patients, subserosal or pedunculated in 85.7%, and ≤5 cm in 71.4%. Bipolar diathermy was the sole method used for hemostasis in 28.6%, and could be characterized as excessive in 85.7%. A 2-layer closure with stitches of the myometrium was performed in just 14.3% of cases. Mean (SD) time between surgery and pregnancy was 1.4 (0.5) years. Uterine rupture occurred at 34 weeks of gestation or later in 85.7%, and during labor in 14.3% of cases. All women survived. Fetal demise was reported in 1 twin pregnancy (both fetuses) with rupture at 24 weeks of gestation. Laparoscopic myomectomy should be performed by adequately trained and experienced surgeons. Excessive use of diathermy for hemostasis should be avoided, and multiple-layer suturing should always be used for repairing the myometrial defect in cases of intramural and subserosal myomas with deep intrusion.

Publication types

  • Review

MeSH terms

  • Adult
  • Electrocoagulation / adverse effects*
  • Female
  • Humans
  • Labor, Obstetric
  • Laparoscopy / adverse effects*
  • Leiomyoma / surgery*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / surgery*
  • Pregnancy Trimester, Second
  • Pregnancy Trimester, Third
  • Suture Techniques / adverse effects
  • Uterine Neoplasms / surgery*
  • Uterine Rupture / etiology*