Highlights from the International Transporter Consortium second workshop

Clin Pharmacol Ther. 2012 Nov;92(5):553-6. doi: 10.1038/clpt.2012.126.


The Second International Transporter Consortium (ITC) Workshop was held with the purpose of expanding on previous white-paper recommendations, discussing recent regulatory draft guidance documents on transporter-drug interactions, and highlighting transporter-related challenges in drug development. Specific goals were to discuss additional clinically relevant transporters (MATEs, MRP2, BSEP) and best-practice methodologies and to re-evaluate ITC decision trees based on actual case studies. The outcome of the workshop will be a series of white papers targeted for publication in 2013.

Publication types

  • Congress

MeSH terms

  • Cooperative Behavior
  • Decision Trees
  • Drug Design*
  • Drug Interactions
  • Humans
  • Internationality
  • Membrane Transport Proteins / metabolism*
  • Pharmaceutical Preparations / metabolism*


  • Membrane Transport Proteins
  • Pharmaceutical Preparations