Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning

Am J Respir Crit Care Med. 2012 Dec 1;186(11):1095-101. doi: 10.1164/rccm.201207-1284CI. Epub 2012 Oct 18.


Carbon monoxide (CO) poisoning is common in modern society, resulting in significant morbidity and mortality in the United States annually. Over the past two decades, sufficient information has been published about carbon monoxide poisoning in the medical literature to draw firm conclusions about many aspects of the pathophysiology, diagnosis, and clinical management of the syndrome, along with evidence-based recommendations for optimal clinical practice. This article provides clinical practice guidance to the pulmonary and critical care community regarding the diagnosis, management, and prevention of acute CO poisoning. The article represents the consensus opinion of four recognized content experts in the field. Supporting data were drawn from the published, peer-reviewed literature on CO poisoning, placing emphasis on selecting studies that most closely mirror clinical practice.

Publication types

  • Comparative Study
  • Consensus Development Conference

MeSH terms

  • Animals
  • Carbon Monoxide Poisoning / diagnosis*
  • Carbon Monoxide Poisoning / mortality
  • Carbon Monoxide Poisoning / prevention & control
  • Carbon Monoxide Poisoning / therapy*
  • Carboxyhemoglobin / analysis*
  • Critical Care / methods
  • Disease Management
  • Dogs
  • Female
  • Humans
  • Hyperbaric Oxygenation / methods
  • Male
  • Oxygen Inhalation Therapy
  • Practice Guidelines as Topic*
  • Primary Prevention / methods*
  • Prognosis
  • Risk Assessment
  • Severity of Illness Index
  • Survival Rate
  • Treatment Outcome
  • United States


  • Carboxyhemoglobin