Delivery, stabilization, and spatiotemporal activation of cargo molecules in cells with positively charged nanoparticles

Chem Commun (Camb). 2012 Dec 4;48(93):11461-3. doi: 10.1039/c2cc35567a. Epub 2012 Oct 23.


Positively charged photodegradable nanoparticles that simultaneously encapsulated various compounds including small and large molecules were prepared. The nanoparticles were internalized to the cell by endocytosis and were stable within the cells for at least 4 days. The encapsulated molecules were released into the cytosol using light stimuli.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Capsules
  • Cell Line, Tumor
  • Drug Stability
  • Endocytosis* / radiation effects
  • Humans
  • Light
  • Nanoparticles / chemistry*
  • Time Factors


  • Capsules