Cutaneous manifestations of Prader-Willi syndrome

Cutis. 2012 Sep;90(3):129-31.


Prader-Willi syndrome (PWS) is a multisystemic genetic disease associated with structural, behavioral, and intellectual disorders. The clinical appearance of PWS includes dysmorphic facial features with almond-shaped eyes, a narrow bifrontal diameter, and a thin upper lip; short stature; central obesity; and small hands and feet. We present a case of a 27-year-old woman with PWS and describe the typical clinical features and cutaneous manifestations of PWS.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Prader-Willi Syndrome / physiopathology*
  • Skin / pathology*
  • Skin Diseases / etiology*
  • Skin Diseases / pathology