Hypersensitivity pneumonitis

Immunol Allergy Clin North Am. 2012 Nov;32(4):537-56. doi: 10.1016/j.iac.2012.08.008. Epub 2012 Sep 13.


Clinical manifestations of hypersensitivity pneumonitis may closely mimic other interstitial lung diseases, and the disease onset is usually insidious. High-resolution computed tomography and bronchoalveolar lavage are the sensitive and characteristic diagnostic tests for hypersensitivity pneumonitis. The relevant antigen to hypersensitivity pneumonitis cannot be identified in up to 20% to 30% of patients. Clinicians should be aware that hypersensitivity pneumonitis must be considered in all cases of interstitial lung disease, and a detailed environmental exposure history is mandatory.

Publication types

  • Review

MeSH terms

  • Alveolitis, Extrinsic Allergic / diagnosis*
  • Alveolitis, Extrinsic Allergic / etiology
  • Alveolitis, Extrinsic Allergic / therapy
  • Diagnosis, Differential
  • Humans
  • Prognosis
  • Smoking